Are you looking for a driven sound, something really clean, or something in between?
I usually crank up the low, mid, and high to 12, and then I roll off the high until I find a sound that's big, clear and without any shrillness (or "shrillity"...is that a word or a George Dubya-ism? ). I've found that the gain set around 4 1/2 - 6(depending on the master volume, of course) gives a nice edgy, but not "driven" sound. A nice natural overdrive, very responsive to picking, cleans up very nicely when picking lightly or when you roll back the volume pedal.
Got a lotta punch for a 15 watt amp. 30lbs...sweet.[This message was edited by Chris Walke on 18 June 2001 at 11:32 AM.]